CD BioSciences provides comprehensive services for the study of biomolecular interactions such as proteins involved in viral research. Similar with surface plasmon resonance (SPR), bio-layer interferometry (BLI) is a label-free binding technique that measures the binding kinetics of biomolecular interactions in real time. BLI has the advantages of high throughput, high sensitivity, low vibration/mechanical noise, and is more cost effective than SPR methods. However, this technique also has shortcomings. Since the technique is relatively new, more issues need to be addressed before full reproducibility can be achieved, and experimental data should be cross-validated with SPR.
BLI technology has a wide range of applications including, but not limited to, affinity and kinetic assays, protein quantification, library screening, drug/antibody screening, drug/antibody discovery, and drug process development optimization. CD BioSciences has accumulated extensive experience from many label-free real-time BLI analysis projects of interacting molecules. Our BLI services have been proven reliable by clients in academia and the pharmaceutical/diagnostic industry. For viral detection studies, we can provide you with.
Buffer: PBS, HEPPS, etc. without organic reagents, without Tris
Protein sample (with antibody): 200ug, concentration >0.5mg/ml
Peptide sample: 200ug, concentration>1mg/ml
Compound small molecule: 200ug, concentration>1mg/ml
Please inform us of your specific BLI technology for virus detection service details, and we can provide customized solutions for different projects.
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