Total Organic Carbon (TOC) is an indirect measure of the amount of carbon in a sample associated with organic compounds or carbon compounds derived from organisms (proteins, lipids, urea, etc.). This differs from elemental carbon (EC) such as graphite or coal and inorganic carbon (IC), which consists of simple compounds including simple carbon oxides (CO and CO₂), carbonates, carbides and Cyanide. The three carbon sources can be distinguished due to the different conditions required for various carbon compounds to degrade into CO. TOC measurements are commonly used to determine environmental water quality and instrument cleanliness testing in the pharmaceutical industry, as well as to quantify biofilm accumulation. Now, CD BioSciences provides you with a variety of biofilm analysis service to meet your scientific research needs.

Our Services

CD BioSciences provides one-stop biofilm TOC analysis services. We offer a variety of methods and equipment to choose from to meet your research needs.

Biofilm TOC Analysis Services Approaches We Offer

• TOC quantification of biofilms from CD BioSciences is typically performed in two steps, including the measurement of total carbon (TC) and IC and use to determine TOC. Biofilms are broken down and ICs are converted to CO₂, usually acidified by heating and detected by infrared spectroscopy. Next, all carbon in the sample is converted to CO₂, usually by thermal oxidation, and TC is then measured. The TOC is then inferred from the difference between these two values ​​(TOC = TC – IC).
• We use instruments such as carbon analyzers to determine accurate methods for sample preparation and quantification. However, the final calculation of TOC is generic and does not depend on the instrument. Because TOC measures the carbon content of the entire biofilm including bacteria and extracellular polymers (EPS).
• Although TOC provides a marker to quantify the amount of biofilm present, we nevertheless correlated this value using direct analytical methods (CFU, cell count, etc.) to generate method-independent values. Furthermore, it has been shown that the amount of carbon in a given volume of cells depends on the health of the bacteria. Therefore, we perform additional associations under each set of conditions and must perform a new standardized protocol or control each time an experiment is performed.

Provided by Clients

Please inform us of your specific biofilm TOC analysis service details, and we can provide customized solutions for different projects.

Service Process

Our Features

Why Choose Us?

CD BioSciences is a professional biofilm technology provider, supporting a variety of biofilm analysis services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. CD BioSciences has accumulated years of quintessence in the field of biofilm detection, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. For more details on how we can support your project with innovation, please feel free to contact us.

• Quantitative Characterization of Biofilms
• Qualitative Characterization of Biofilms
• Biofilm Total Protein Determination
• Quantitative Analysis of Bacteria in Biofilms
• Biofilm Genomics and Metagenomics Services
• Biofilm Transcriptomics Services
• Biofilm Proteomics Services
• Biofilm Metabolomics Services
• Interaction Analysis of Biofilm Community
• Biofilm Interface Analysis
• Feature Analysis of Biofilm Formation
• Biofilm Microelectrode Analysis
• Biofilm Interaction Analysis
• Biofilm Volume and Morphology Analysis
• Biofilm ATP Bioluminescence Analysis
• Biofilm Imaging Services
• Biofilm Optical Coherence Tomography Analysis
• Biofilm Optical Density (OD) Analysis