Microbial biofilms are complex, self-organizing communities of bacteria that use physiological cooperation and spatial organization to improve their metabolic efficiency and resistance to local environmental changes. These properties make biofilms attractive targets for engineering, particularly for the production of chemicals such as pharmaceutical ingredients or biofuels, with the potential for significantly higher yields and lower maintenance costs. Biofilms are also a major cause of persistent infections, and a better understanding of their organization may lead to new destructive strategies. Computational modeling can help address this challenge by predicting the behavior of synthetic biofilms prior to their construction. Now, CD BioSciences provides you with a variety of biofilm modeling services to meet your scientific research needs.
Biofilm Modeling Service Approaches We Offer
- Biofilm Homology Modeling Service
CD BioSciences' homology modeling services can help researchers understand the structural properties of biofilms and can be used for drug screening, discovery of potential disease treatments, or target drug interaction studies. Homology modeling is a practical method for predicting structure from sequences.
- Gram-negative Bacterial Outer Membrane Construction Service
We developed a coarse-grained outer film force field that is computationally affordable to simulate dynamic processes on physiologically relevant time scales. The force field is benchmarked against available experimental and atomic simulation data to obtain properties such as film thickness, residue density distribution, area per lipid, gel to liquid crystal phase transition temperature, and ordering parameters.
- Biofilm Formation Simulation Service
CD BioSciences uses dissipative particle dynamics (DPD) simulation methods to model the salient features of biofilm formation. In addition, we offer professional services for analysis of results, image processing, and data aggregation.
- Construction Services for Discrete Difference Models
CD BioSciences has developed a fully quantitative 2D and 3D method for biofilm growth and structure formation. Our model combines flow over irregular biofilm surfaces, convective and diffusive mass transfer of substrates, bacterial growth and bacterial diffusion.
- Modeling Services for Geometric Heterogeneity in Biofilms
CD BioSciences provides state-of-the-art computational models for biofilm morphology in a hydrodynamic environment and has built these models for high performance computing applications. We provide data parallelism in the models and solution algorithms.
- Computational Simulation Service for Early Biofilm Development
CD BioSciences models the early stages of bacterial biofilm formation through single cell-based computer simulations. We can show the analysis of microscopic images of early biofilm formation of Gram-negative bacteria at different diffusion rates and thus compare with simulated results.
- Computational Modeling Services for Synthetic Biofilms
We provide a computational method for simulating synthetic microbial biofilms that combines three-dimensional biophysical models of individual cells with models of genetic regulation and intercellular signaling.
Our Advantages
- Molecular dynamics simulations save a lot of labor costs
- Short and fast computational cycles
- Requires far less money than biological or chemical experiments.
- High computational accuracy
Provided by Clients
Please inform us of your specific biofilm modeling service details, and we can provide customized solutions for different projects.
Service Process
Our Features
- CD BioSciences provides customers with proven solutions for specificbiofilm modeling service in a user-friendly, fast, accurate and cost-effective format.
- CD BioSciences has established a proven biofilm construction technology platform for a variety of applications. We'll help you design the right solutions to help you in your biofilm research.
- We have accumulated many years of essence in the field of biofilm construction, helping customers to speed up project development and improve the overall success rate of the project.
Why Choose Us?
CD BioSciences is a professional biofilm technology provider, supporting a variety of biofilm modeling services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. CD BioSciences has many years of experience in biofilm technology. If you would like to know more details about biofilm service, please feel free to contact us. We will ensure to provide you with efficient and high-quality experimental outsourcing services.
For research use only, not intended for any clinical use.
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