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Hydrophobic Interaction Analysis of Biofilm System

The phenomenon in which hydrophobic groups aggregate close to each other to avoid water is called hydrophobic interaction. Hydrophobic interactions are the main driver of protein folding. Proteins are stable in water when the hydrophobic side chains in the protein aggregate inside the protein, rather than being solvated by water. Hydrophobic interactions play a major role in maintaining protein conformation because water molecules interact more strongly with each other than with other nonpolar molecules. Non-polar side chains aggregate into the interior of protein molecules to avoid water. The hydrophobic properties within the molecule explain not only the aggregation of hydrophobic residues, but also the stabilization of helices and sheets. Now, we use computer-aided methods to provide biofilm secondary structure analysis services to help customers complete biofilm related research.

Our Services

CD BioSciences provides one-stop hydrophobic interaction analysis of biofilm system service. We offer a variety of methods and software to choose from to meet your research needs.

Specific Hydrophobic Interaction Analysis Approaches We Offer

  • We provide energy decomposition service. In the energy decomposition service, we decompose the binding free energy into van der Waals interaction, electrostatic interaction, etc. Through analysis, it can be judged that the hydrophobic interaction contributes more to the interaction between the biofilm and other molecules. The force is also the electrostatic interaction force.
  • In addition, we also provide the area of the protein surface accessible by the solvent, commonly referred to as solvent accessible surface (SAS, solvent accessible surface). The solvent accessible surface area can be further subdivided into hydrophilic SAS and hydrophobic SAS. In addition, combined with some empirical parameters, SAS can also be used to estimate the free energy of solvation.

Samples Requirements

  • The initial structure of the PDB ID (if molecular dynamics simulation service is required)
  • MD simulation raw data

Provided by Clients

Please inform us of your specific hydrophobic interaction analysis service details, and we can provide customized solutions for different projects.

Service Process

Service Process

Our Features

  • CD BioSciences has a professional biofilm platform. We have a variety of methods to provide you with hydrophobic interaction analysis of biofilm system service. You can choose the appropriate method according to your scientific research needs.
  • We use advanced technology platforms for biofilm services. Our experienced scientists have created a comprehensive platform to measure the size distribution of different biological particles and analyze their morphology at the same time.


  1. Related experimental results raw data
  2. Hydrophobic interaction analysis of biofilm system results
  3. Free energy decomposition results
  4. Solvent accessible surface analysis results
  5. Image and result analysis
  6. Summary of relevant calculation parameters

Why Choose Us?

CD BioSciences has a lot of expertise and rich experience in the research of biofilm. We have established a comprehensive and complex biofilm platform. Our mission is to provide reliable and high-quality services to provide our customers with strong support in the biofilm services. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

For research use only, not intended for any clinical use.
Related Services:

CD BioSciences is a specialized company providing biofilm services with expertise in the intersection of chemistry and biophysics. Our platform offers advanced technologies to meet all your biofilm needs.

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