In continuum systems, most numerical methods aim to discretize ordinary or partial differential equations that control mechanical, chemical and biological processes, while commonly used methods include finite element method (FEM), finite difference method (FDM), finite Volumetric Method (FVM) etc. In particular, computational models provide insights from experiments to verify the mechanical properties of biofilms. As one of the most commonly used computational mechanics methods, finite elements subdivide the computational domain into smaller subdomains, called finite elements, which are implemented by meshing, and the extended finite element (XFEM) method, which allows the study of boundary layer behavior and linearization of biofilm growth in elliptic equations. CD BioSciences use computer-aided methods to provide XFEM service to help customers complete biofilm related research.

Specific XFEM Approaches We Offer

• CD BioSciences provides XFEM services, which can not only combine diffusion reactions, but also show the relationship between colony morphology and nutrient deficiency;
• We use the level set method, an algorithm widely used in multiphase flow calculations, to simulate the growth of biofilms.
• Fluid-structure interactions are important when using FEM to study biofilm detachment under fluid flow. We can also use the Time Discontinuous Galerkin (TDG) method as a solution strategy for multidimensional multispecies biofilm growth models. In short, the XFEM method combined with multiphysics accurately describes the mechanical behavior of biofilms as a continuous method for computing biofilms.
• In addition, we provide professional results analysis, image processing, data aggregation and other services.

Provided by Customers

Please inform us of your specific biofilm XFEM service details, and we can provide customized solutions for different projects.      

Service Process

Our Features

Deliverables

1. Related experimental results raw data
2. XFEM results
3. XFEM results analysis
4. Image and result analysis
5. Interaction and movement details
6. Summary of relevant calculation parameters

Why Choose Us?

CD BioSciences is a company that provides professional and comprehensive biofilm services. We have years of experience to meet your specific project needs in using biofilm research to add value to your research projects. CD BioSciences can provide you with personalized solutions to help you thrive every step of the way around your interest in your workflow. If you would like to know more details about biofilm service, please feel free to contact us.

References

1. Hanfeng Zhai, et al. Multiscale Computational Modeling of Biofilm. 2022
2. Feng, D, Neuweiler, I. & Nackenhorst, U. A spatially stabilized TDG based finite element framework for modeling biofilm growth with a multi-dimensional multi-species continuum biofilm model. Comput Mech. 2017, 59, 1049–1070

• Biofilm Computational Construction Service
• Biofilm Molecular Dynamics Simulation Service
• Stability Test of Biofilm System
• RMSF Analysis of Biofilm System
• Gyration Radius Analysis of Biofilm System
• Binding Mode Analysis of Biofilm System
• Secondary Structure Analysis of Biofilm System
• Energy Analysis of Biofilm System
• Hydrophobic Interaction Analysis of Biofilm System
• Free Energy Landscape Analysis of Biofilm System
• Biofilm Conformational Principal Component Analysis
• Biofilm Ramachandran Plots Analysis
• Cluster Analysis of Biofilm System
• SAS Analysis Service of Biofilm System
• Energy Decomposition Analysis of Biofilm System
• Electrostatic Interaction Analysis of Biofilm System
• Biofilm Virtual Screening Service
• Computational Modeling of Early-Stage Biofilm Formation
• Biofilm CGMD Service
• Biofilm DPD Service
• Biofilm DEM Service
• Biofilm SPH Service
• Other Biofilm MD Serivce
• Biofilm Homology Modeling Serivce
• Gram-negative Bacterial Outer Membrane Construction Service
• Biofilm Formation Simulation Service
• Construction Services for Discrete Difference Models
• Modeling Services for Geometric Heterogeneity in Biofilms
• Computational Simulation Service for Biofilm Development
• Computational Modeling Service for Synthetic Biofilms
• Biofilm MD Results Analysis Services
• Biofilm Multiscale Computational Modeling Service
• Biofilm Modeling Service