Application of Biofilm in Dermatology
Introductions
Biofilms represent dense aggregates of microorganisms encased in a self-produced extracellular polymer matrix that helps them to adhere to biotic and abiotic surfaces, thus conferring them a survival advantage under unfavorable conditions. The stages of biofilm formation are complex and it is important to understand this as their role in various skin diseases is constantly uncovered. They pose a unique challenge to treating clinicians due to their chronic persistence, their inability to be detected by conventional culture techniques, and their resistance to standard antimicrobial treatments.
Application of Biofilm in Dermatology
Open wounds increase the chances of biofilm formation due to the lack of skin protection. Biofilms can form very rapidly on wounds in as little as 8 hours. Biofilm prevention and treatment can be achieved by repeated wound debridement or debridement to remove non-viable tissue, thereby reducing the surface area for biofilm formation. Low-frequency ultrasound, laser and photodynamic therapy (PDT) are alternative non-invasive methods to achieve biofilm breakdown and promote wound healing.
It is hypothesized that the localization of biofilm in the sinus and funnel sections is due to the abundance of keratin fragments that may provide foci for commensal cocci and anaerobes in these lesions. Therefore, it is suggested that for better disease control, a combination of pharmacological treatment with early surgical excision or simple removal of the roof may be attempted.
Biofilms play a major role in the pathogenesis of atopic dermatitis. Biofilm-induced sweat duct obstruction may be the cause of inflammation and pruritus in atopic dermatitis. It is more common in normal skin and is related to its pathogenesis.
Biofilms are associated with the pathogenesis of prickly heat, and they lead to sweat gland occlusion. Therefore, biofilms have been found to be associated with a variety of skin diseases as described.
Our Solutions About Biofilm in Dermatology
Biofilms are usually resistant to conventional antiseptics and antibiotics. The actual treatment depends on the underlying disease it is involved in. Therefore, the treatment may aim to disrupt the biofilm by disrupting its extracellular matrix, including wound debridement, early surgical excision, pharmacological interruption of the biofilm microenvironment, and various physical modalities including pulsed ultrasound and laser, so that antimicrobial agents can better access and kill the microorganisms. CD BioSciences offer you professional biofilm removal services, including physical biofilm elimination technology services, chemical biofilm eradication technology services, electrochemical biofilm elimination services, drug delivery method biofilm elimination services, etc.
Our Related Services
- Biological Biofilm Eradication Technical Services
- Drug Delivery Methods Biofilm Elimination Services
- Structural Modulation Biofilm Elimination Services
- Endoscopic Biofilm Eradication Services
- Physical Biofilm Eradication Technical Services
- Chemical Biofilm Eradication Technical Services
Why Choose Us?
CD BioSciences provides professional biofilm service to meet the scientific research needs of customers. CD BioSciences relies on world-class technical expertise, we provide customers with the highest quality one-stop biofilm-related services, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.
For research use only, not intended for any clinical use.
Related Services:
