In nature, most bacteria are found as part of sessile communities associated with surfaces and are embedded in polymeric extracellular matrices called biofilms. Interest in biofilms stems from their involvement in persistent infection processes and biodegradation of materials, but also from their potential application as efficient biocatalysts for the elimination of contaminants or for the production of chemicals. Most bacteria form organized sessile communities called biofilms. Their prevalence and relevance have stimulated the development of efficient mathematical models capable of predicting the evolution and characteristics of biofilms under different conditions. CD BioSciences use computer-aided methods to provide computational simulation service for early biofilm to help customers complete biofilm related research.

Specific Computational Simulation Approaches We Offer

• CD BioSciences models the early stages of bacterial biofilm formation through single cell-based computer simulations.
• CD BioSciences can show the analysis of microscopic images of early biofilm formation of Gram-negative bacteria at different diffusion rates and thus compare with simulated results.
• Competition between diffusion and growth rates is a key aspect of the formation of stable biofilm microflora. Our model can be a good predictor of microflora morphology during biofilm development.
• In addition, we provide professional results analysis, image processing, data aggregation and other services.

Provided by Customers

Please inform us of your specific computational simulation service for computational simulation service for biofilm development details, and we can provide customized solutions for different projects.

Service Process

Our Features

Deliverables

1. Related experimental results raw data
2. Simulation results
3. Image and result analysis
4. Interaction and movement details
5. Summary of relevant calculation parameters

Why Choose Us?

CD BioSciences offers computational simulation service for biofilm development to researchers who wish to benefit from this technology. With talented biofilm technologists and state-of-the-art facilities, we offer integrated, ready-to-use solutions. We are happy to discuss your project and the potential of applying biofilm service with you. Our excellent technology platform can realize a variety of biofilm technology services and solve all difficulties encountered in research for customers. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.  

Reference

1. Hanfeng Zhai, et al. Multiscale Computational Modeling of Biofilm. 2022

• Biofilm Computational Construction Service
• Biofilm Molecular Dynamics Simulation Service
• Stability Test of Biofilm System
• RMSF Analysis of Biofilm System
• Gyration Radius Analysis of Biofilm System
• Binding Mode Analysis of Biofilm System
• Secondary Structure Analysis of Biofilm System
• Energy Analysis of Biofilm System
• Hydrophobic Interaction Analysis of Biofilm System
• Free Energy Landscape Analysis of Biofilm System
• Biofilm Conformational Principal Component Analysis
• Biofilm Ramachandran Plots Analysis
• Cluster Analysis of Biofilm System
• SAS Analysis Service of Biofilm System
• Energy Decomposition Analysis of Biofilm System
• Electrostatic Interaction Analysis of Biofilm System
• Biofilm Virtual Screening Service
• Computational Modeling of Early-Stage Biofilm Formation
• Biofilm CGMD Service
• Biofilm DPD Service
• Biofilm DEM Service
• Biofilm SPH Service
• Biofilm XFEM Service
• Other Biofilm MD Serivce
• Biofilm Homology Modeling Serivce
• Gram-negative Bacterial Outer Membrane Construction Service
• Biofilm Formation Simulation Service
• Construction Services for Discrete Difference Models
• Modeling Services for Geometric Heterogeneity in Biofilms
• Computational Modeling Service for Synthetic Biofilms
• Biofilm MD Results Analysis Services
• Biofilm Multiscale Computational Modeling Service
• Biofilm Modeling Service