CD BioSciences provide computational models of biofilms and bacterial cells, offering perspectives on the various properties of biofilms and their potential as engineered living materials (ELMs). We can start with molecular systems and work from the bottom up to the mesoscale and then to the continuum, focusing on mesoscale algorithms such as dissipative parametric dynamics (DPD) and individual-based modeling (IbM).

Biofilm Multiscale Computational Modeling Service Approaches We Offer

• Biofilms are bacterial communities adhering to surfaces, accommodating and aggregating together, and exhibiting multi-scale biomechanical behavior. In this section, we provide a multiscale computational modeling approach for simulating biofilms, focusing on mechanical properties and their application or potential as engineered living materials (ELMs).
• We provide all-atom molecular dynamics (MD) techniques for molecular modeling of biofilms, mainly on chemical and biological mechanisms, followed by mesoscopic approaches, namely dispersive particle dynamics (DPD) and lattice Boltzmann engineering; further bottom-up smooth particle hydrodynamics (SPH) and discrete element method (DEM) modeling of biofilms.
• Note that DEM, which can also be referred to as individual-based modeling (IbM) and agent-based modeling (ABM), is one of the most adopted methods for biofilm modeling due to its accurate description and coupling of biological processes, chemical reactions and mechanical properties, and is one of the most promising techniques for connecting multi-scale multi-physical properties.

Our Advantages

• Molecular dynamics simulations save a lot of labor costs
• Short and fast computational cycles
• Requires far less money than biological or chemical experiments.
• High computational accuracy

Our Advantages

Provided by Clients

Please inform us of your specific biofilm multiscale computational modeling service details, and we can provide customized solutions for different projects.  

Service Process

Our Features

Why Choose Us?

CD BioSciences is a professional biofilm technology provider supporting a wide range of biofilm multiscale computational modeling services. We are able to perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. We have accumulated years of quintessence in the field of biofilm MD, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. If you would like to know more details about biofilm service, please feel free to contact us. We will ensure to provide you with efficient and high-quality experimental outsourcing services.

• Biofilm Computational Construction Service
• Biofilm Molecular Dynamics Simulation Service
• Stability Test of Biofilm System
• RMSF Analysis of Biofilm System
• Gyration Radius Analysis of Biofilm System
• Binding Mode Analysis of Biofilm System
• Secondary Structure Analysis of Biofilm System
• Energy Analysis of Biofilm System
• Hydrophobic Interaction Analysis of Biofilm System
• Free Energy Landscape Analysis of Biofilm System
• Biofilm Conformational Principal Component Analysis
• Biofilm Ramachandran Plots Analysis
• Cluster Analysis of Biofilm System
• SAS Analysis Service of Biofilm System
• Energy Decomposition Analysis of Biofilm System
• Electrostatic Interaction Analysis of Biofilm System
• Biofilm Virtual Screening Service
• Computational Modeling of Early-Stage Biofilm Formation
• Biofilm CGMD Service
• Biofilm DPD Service
• Biofilm DEM Service
• Biofilm SPH Service
• Biofilm XFEM Service
• Other Biofilm MD Serivce
• Biofilm Homology Modeling Serivce
• Gram-negative Bacterial Outer Membrane Construction Service
• Biofilm Formation Simulation Service
• Construction Services for Discrete Difference Models
• Modeling Services for Geometric Heterogeneity in Biofilms
• Computational Simulation Service for Biofilm Development
• Computational Modeling Service for Synthetic Biofilms
• Biofilm MD Results Analysis Services
• Biofilm Modeling Service