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Construction Services for Discrete Difference Models

Modeling the structural development of biofilms is a formidable challenge due to the complex interplay between many processes. Biofilm development is determined by "positive" processes such as cell attachment, cell division, and polymer formation, leading to volume expansion of biofilms, while "negative" processes, such as cell detachment and cell death, lead to biofilm contraction. By changing the balance between these two types of processes, biofilms with different structural properties such as porosity, compactness or surface roughness can be formed. CD BioSciences use computer-aided methods to provide construction services for discrete difference models to help customers complete biofilm related research.

Specific Construction Approaches We Offer

  • CD BioSciences has developed a fully quantitative 2D and 3D method for biofilm growth and structure formation.
  • Our model incorporates flow over irregular biofilm surfaces, convective and diffusive mass transfer of substrates, bacterial growth, and bacterial diffusion.
  • Upon customer request, our model will also include biofilm detachment mechanisms due to biofilm deformation stress. Models can accommodate arbitrarily shaped carrier surfaces, as well as multi-species and multi-matrix biofilms.

Our Service Process

Our Service Process

  • First, a hydrodynamic step is performed. The momentum transfer and continuity equations are solved to find the flow field variables
  • The second step uses the flow rate U just calculated to solve for mass transfer of soluble components, conyectjye-djffusiye.
  • The new biomass S content of each grid element. Cx, is calculated by using the Monod and Herbert-Pirt equations, including the previously calculated substrate concentration at steady state.
  • As the biomass grows, it must be redistributed in space.
  • The separation step can also be performed before redistribution, since the separation time constant is in the same range as the growth time.

Provided by Customers

Please inform us of your specific construction services for discrete difference models details, and we can provide customized solutions for different projects.

Service Process

Service Process

Our Features

  • CD BioSciences has a proven, advanced biofilm technology platform that is constantly being improved to ensure that we can provide accurate, sensitive, and rapid analytical results for our customers.
  • CD BioSciences offers a variety of methods to meet your needs. We specialize in discrete difference models construction with very competitive prices and fast turnaround times.
  • We offer 24/7 round-the-clock service. Relatively faster service efficiency and more competitive service prices in the industry represent our commitment to provide better service to our customers.



  1. Related experimental results raw data
  2. Simulation results
  3. Image and result analysis
  4. Interaction and movement details
  5. Summary of relevant calculation parameters

Why Choose Us?

CD BioSciences is a professional biofilm technology provider, supporting a variety of biofilm discrete difference models construction services. We can perform individual tests at the most precise level, as well as design and complete a suite of services as a solution to the subject project. CD BioSciences has accumulated years of quintessence in the field of biofilm eradication, helping our clients accelerate drug discovery and development and improve the overall success rate of their projects. For more details on how we can support your project with innovation, please feel free to contact us.


  1. Hanfeng Zhai, et al. Multiscale Computational Modeling of Biofilm. 2022
For research use only, not intended for any clinical use.
Related Services:

CD BioSciences is a specialized company providing biofilm services with expertise in the intersection of chemistry and biophysics. Our platform offers advanced technologies to meet all your biofilm needs.

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