Biolayer interferometry (BLI) is a non-labeling technique based on the principle of optical interference. It has the advantages of simple operation, short detection time, low sample consumption, and direct participation in analysis and detection without manual labeling. By monitoring the optical interference signal in real time, BLI technique can be widely used in the analysis and rapid detection of biomolecular interactions. CD BioSciences provide affinity analysis between molecules service to help customers complete biofilm related research.
When BLI is applied to kinetic constant determination experiments, the commonly used biosensors mainly include SA, SSA, AR2G, APS, AHC and AMC, etc. Each biosensor is suitable for different biological samples, and the requirements for using different biosensors are different. For example, SSA is only suitable for detecting small molecules, while SA is used to solidify biotinylated proteins, antibodies, compounds and nucleic acids to detect large molecules interacting with them, and AHC can directly solidify human antibodies to detect the molecules interacting with them.
Please inform us of your specific affinity analysis between molecules service system details, and we can provide customized solutions for different projects.
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