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BLI Technology for Molecular Interaction Assay

Our BLI platform is an advanced technology for non-labeled, real-time monitoring of the full range of quantitative analysis of biomolecular interactions and protein concentration determination. The Dip and Read assay allows easy processing of crude, unpurified samples to study the interaction and binding kinetics of sample molecules in real biological environments. For example: analysis of unfiltered cell culture supernatants and lysates; study of molecular interactions in biological environments; direct affinity analysis of viral or virus-like particle samples. CD BioSciences provides professional BLI technology for molecular interaction assay service to help customers complete biofilm related research.

Specific BLI Technology for Molecular Interaction Assay Approaches We Offer

Antibody and antibody fragment identification

  • Detection of Ka,Kd and KD of antigen-antibody binding
  • Affinity sorting and dissociation rate sorting of crude supernatant samples
  • Antibody engineering and affinity maturation

Protein-protein interactions, protein-peptide interactions

  • Structure-effect relationship and mechanism of action study
  • Structural isomer dynamics analysis
  • Wild-type and mutant analysis
  • Protein-DNA interactions, protein-RNA interactions.
  • Analysis of transcription factor interactions
  • RNA regulation mediated by RNA binding proteins

Mechanisms of translation regulation

  • Protein-lipid interactions.
  • Protein-liposome interactions
  • Analysis of membrane protein dynamics

Virus and vaccine studies

  • HIV envelope protein studies
  • Evolution of viral binding selectivity
  • Development of viral antibodies

Protein-small molecule interactions

  • Non-labeled assays with a lower limit of molecular weight detection of 150Da
  • Rapid compound library screening
  • Binding parameters including Ka, Kd and KD

Immunogenicity analysis

  • High and low affinity anti-drug antibody (ADA) determination by bridging or direct methods
  • Residual protein A assay
  • For protein A and its bio-analogues such as MabSelect SuRe assay
  • CHO host cell protein assay
  • Rapid, high-throughput detection of CHO host cell protein residues


In order to provide you with accurate and efficient quotation, please contact our customer service personnel, we will be the first time to do detailed communication with you project and provide technical solutions.

Provided by Clients

Please inform us of your specific BLI technology for molecular interaction assay details, and we can provide customized solutions for different projects.     

Service Process

Service Process

Our Features

  • CD BioSciences has established a proven biofilm technology platform for a variety of applications. We'll help you design the right biofilm technology service to aid your scientific research.
  • CD BioSciences is a leading biofilm technology company offering a trusted suite of services and solutions, especially with our extensive experience in biofilm testing.
  • With our talented people and years of experience, we can fully meet your project requirements and budget in exploring fluorescent markers of biofilms.



  1. Related experimental results raw data
  2. Polysaccharides detection results
  3. Experimental report
  4. Data analysis
  5. Image and result analysis
  6. Summary of relevant calculation parameters

Why Choose Us?

CD BioSciences is a company that provides professional and comprehensive biofilm services. We have years of experience to meet your specific project needs in using biofilm research to add value to your research projects. CD BioSciences can provide you with personalized solutions to help you thrive every step of the way around your interest in your workflow. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

For research use only, not intended for any clinical use.
Related Services:

CD BioSciences is a specialized company providing biofilm services with expertise in the intersection of chemistry and biophysics. Our platform offers advanced technologies to meet all your biofilm needs.

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