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Biofilm CGMD Service

Coarse-grained simulation aims to simulate the behavior of a complex system using its coarse-grained (simplified) representation. Coarse-grained models are widely used for molecular modeling of biomolecules at various granularity levels. Various coarse-grained models have been proposed. They are usually devoted to computational modeling of specific molecules: proteins, nucleic acids, lipid membranes, carbohydrates or biological membranes. Coarse-grained models have been used practically in molecular dynamics simulations. CD BioSciences use computer-aided methods to provide CGMD service to help customers complete biofilm related research.

Difference Between MD and CDMD

Intracellular interaction processes (such as protein-protein docking, ligand-binding site conformational changes, macromolecular folding, etc.) often involve a large number of different types of biomolecules and the collective motion of biomolecules, usually lasting longer than a few microseconds to a few milliseconds . Traditional all-atom simulations are difficult to achieve. Therefore, reducing the degrees of freedom of the simulated system by simplifying the details of all-atom simulations has created a long-standing large-scale simulation method—the coarse-grain (CG) simulation method.

Specific CGMD Approaches We Offer

Specific CGMD Approaches We Offer

  • Following MD, coarse-grained MD (CGMD), a method of using a simplified representation of a system to simulate its behavior, is widely used in biochemical and biomolecular systems, especially for studying the biochemical properties of bacterial cells. CGMD is primarily used to model systems at the micrometer scale, approximately the scale of a single bacterial cell, as shown in Figure 1.
  • We provide computational models of biofilms and bacterial cells, providing insights into the various properties of biofilms and their potential as engineered biomaterials.
  • Biofilms are bacterial communities attached to surfaces that can accommodate and aggregate, exhibiting multiscale biomechanical behavior. We provide multiscale computational modeling approaches for simulating biofilms, focusing on mechanical properties and their application or potential as engineered biomaterials (ELMs).

Provided by Clients

Please inform us of your specific biofilm CGMD service details, and we can provide customized solutions for different projects.      

Service Process

Service Process

Our Features

  • CD BioSciences can provide customers with high-quality biofilm CGMD services. We have accumulated rich experience in biofilm services.
  • CD BioSciences has a deep reserve of biofilm services, and our scientists can provide customers with more systematic biofilm-related service.
  • Our technical team can tailor the biofilm service plan for you, and provide affordable and high-quality technical services.


  1. Related experimental results raw data
  2. CGMD results
  3. CGMD results analysis
  4. Image and result analysis
  5. Interaction and movement details
  6. Summary of relevant calculation parameters


Why Choose Us?

CD BioSciences provides professional biofilm CGMD services. We will meet the specific needs of customers on time and on budget. CD BioSciences relies on world-class technical expertise, we provide customers with the highest quality one-stop service, including the development of solutions according to different scientific research needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.  


  1. Hanfeng Zhai, et al. Multiscale Computational Modeling of Biofilm. 2022
  2. Kmiecik, Sebastian, Gront, et al. Coarse-Grained Protein Models and Their Applications. 2016, 116, 14, 7898–7936.
For research use only, not intended for any clinical use.
Related Services:

CD BioSciences is a specialized company providing biofilm services with expertise in the intersection of chemistry and biophysics. Our platform offers advanced technologies to meet all your biofilm needs.

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