The BLI technique refers to the determination of biomolecular interactions. The technique is an optical analysis method for analyzing the interference pattern of white light reflected from two surfaces: the internal reference layer and the precipitated protein layer on the biosensor tip. The change in the interference pattern is caused by any change in the number of molecules bound to the biosensor tip. In this case, interactions can be measured in real time, providing the ability to monitor binding specificity, ratio of binding and dissociation, concentration, fidelity and accuracy. In addition, only molecules bound to or dissociated from the biosensor can alter the interference pattern and generate a response profile on the BLI system. CD BioSciences provides professional bio-layer interferometry (BLI) service to help customers complete biofilm related research.

Specific Bio-Layer Interferometry (BLI) Approaches We Offer

• Based on an advanced bio-layer interference (BLI) technology platform built over many years and experienced experts in drug discovery, CD BioSciences can provide unparalleled BLI services to meet all your needs.
• CD BioSciences offers high quality BLI services to identify interactions between identified protein targets and fragments, a critical step in drug discovery. BLI is a useful tool for fragment screening in the drug discovery process. Compared to other methods, BLI offers significant advantages in that it can significantly reduce the false positive rate.
• CD BioSciences can provide protein interaction services using BLI technology to screen for suitable drug candidates or any other protein interactions you require.

Provided by Clients

Please inform us of your specific bio-layer interferometry (BLI) service details, and we can provide customized solutions for different projects.

Service Process

Our Features

Deliverables

1. Related experimental results raw data
2. Bio-Layer Interferometry (BLI) results
3. Experimental report
4. Data analysis
5. Image and result analysis
6. Summary of relevant calculation parameters

Applications

• Protein quantitation in the analyte
• Binding specificity and cooperativity determination
• Affinity and Kinetics analysis (measurement of reaction rate constants (Kobs, Ka, Kd)

Why Choose Us?

CD BioSciences provides professional bio-layer interferometry (BLI) services to meet the scientific research needs of customers. CD BioSciences relies on world-class technical expertise, we provide customers with the best quality one-stop bio-layer interferometry (BLI) services, including the development of experimental procedures according to different experimental needs. Please feel free to contact us for more detailed information, our scientists will tailor the most reasonable plan for your project.

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