One of the most important advances in the study of biofilm structure, function, and dynamics has been the ability to analyze and characterize biofilms using imaging techniques to characterize the structure-function relationships of microbial cells, and miniaturization studies to characterize biofilms physical and heterogeneous properties. Advances in chemistry and molecular biology have also improved the ability to image biofilms in three dimensions. In particular, the use of fluorescent proteins and fluorescent probes allows imaging by multiple fluorescent dyes for simultaneous analysis of individual biofilm components. Another new development in imaging techniques is super-resolution microscopy, which uses photoactivatable fluorescent proteins or probes to image at a much higher resolution than conventional light microscopy. It is likely that high-resolution methods will soon find application in biofilm research. Now, CD BioSciences provides you with a variety of biofilm imaging service to meet your scientific research needs.

Our Services

CD BioSciences provides one-stop biofilm imaging service. We offer various methods to choose from to meet your research needs.

Biofilm Imaging Services Approaches We Offer

Technique	Experimental features	Types and modifications	Application and examples
Fluorescent protein	Multiple functions Genetically encoded No need for fixation Real-time detection Molecular techniques need to be developed for organisms Cell physiology may be altered	Photoconvertable Photoswitchable FP timer FRET/BRET Oxygen-independent FP	Cell differentiation Cell tracking Expression profile Protein localization Activity indicator High-resolution imaging
Fluorescent in situ hybridization	High target specificity No genetic modification necessary Exogenous addition Fixation of sample is necessary	Peptide nucleic acid probe CLASI-FISH CARD-FISH MAR-FISH	Cell localization mRNA expression profile High-resolution imaging
Fluorescent stain	Exogenous addition Can be specific for biomolecules and cellular components	FM1-43 CTC BrdU-fluorescent antibody Calcofluor TOTO-1	Activity indicator Viability indicator
Fourier transform infrared spectrometry (FT-IR)	Nondestructive Real-time detection	ATR/FT-IR SR-FTIR	Chemical composition of EPS Quantification of biomass Spatial distribution of biomolecules
Raman spectrometry	Nondestructive Real-time detection	Raman microscopy SERS	Chemical composition of EPS Quantification of biomass Spatial distribution of biomolecules
Nuclear magnetic resonance microscopy	Nondestructive Real-time detection	Use of isotope-labeled substrates	Water flow and water dynamics of EPS Dynamics of metabolites

Provided by Clients

Please inform us of your specific biofilm imaging service s details, and we can provide customized solutions for different projects. 

Service Process

Our Features

Why Choose Us?

CD BioSciences is a specialized biofilm technology company with the ability to specialize in services such as biofilm imaging in an efficient and precise manner. With outstanding staff, state-of-the-art technology and facilities, CD BioSciences is able to provide you with a comprehensive range of biofilm imaging technologies. If you have this need, please feel free to contact us.

• Quantitative Characterization of Biofilms
• Qualitative Characterization of Biofilms
• Biofilm Total Protein Determination
• Quantitative Analysis of Bacteria in Biofilms
• Biofilm Genomics and Metagenomics Services
• Biofilm Transcriptomics Services
• Biofilm Proteomics Services
• Biofilm Metabolomics Services
• Biofilm TOC Analysis Services
• Interaction Analysis of Biofilm Community
• Biofilm Interface Analysis
• Feature Analysis of Biofilm Formation
• Biofilm Microelectrode Analysis
• Biofilm Interaction Analysis
• Biofilm Volume and Morphology Analysis
• Biofilm ATP Bioluminescence Analysis
• Biofilm Optical Coherence Tomography Analysis
• Biofilm Optical Density (OD) Analysis